MicroRNA and Cancer

MicroRNAs (miRNAs) are short, non-coding RNA molecules, typically 20–24 nucleotides in length, that play a crucial role in regulating gene expression across nearly all biological pathways in mammals. Their involvement in cancer has been increasingly recognized through studies in cell cultures and animal models. miRNAs regulate several critical cancer-related processes, including DNA damage response, cell cycle regulation, and apoptosis.

Emerging evidence supports their clinical relevance, with miRNAs being explored and implemented as diagnostic and prognostic biomarkers, aiding in patient stratification. Moreover, they hold potential as therapeutic agents and targets, paving the way for innovative strategies in personalized cancer treatment.

 

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