MicroRNA and Cancer


MicroRNAs (miRNAs) are short non-coding RNAs of 20–24 nucleotides that plays vital role in virtually mammals and all biological pathways. Involvement of microRNAs in cancer, which have evolved from the study of animal model systems and cell culture.  It involves in the regulation of key cancer-related pathways, such as DNA damage response, cell cycle control and the microRNA molecules are already entering into the clinic as prognostic biomarkers and diagnostic for patient stratification and also as agents and therapeutic targets.



 


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